MOPS Buffer


Cryopreservation media | Cell culture media | Chromatography | Cosmetics | Electrophoresis | Protein purification
Packaging Options
  • 40 kg drum
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Assay (titr.): ≥ 99.5% | CAS No: 1132-61-2 | Useful pH range: 6.5 – 7.9 

Hopax is a manufacturer and supplier of MOPS (CAS 1132-61-2), a zwitterionic biological buffer often used as a buffering agent in biological and biochemical research.

Uses of MOPS Buffer:

  • Similarly to MES Buffer, this Good's Buffer lacks the capability to form a complex with most metal ions, therefore it is recommended for use as a noncoordinating buffer in solutions with metal ions
  • Used in cell culture media for yeast, bacteria and mammalian cells
  • Used for separating RNA in agarose gels
  • Used as a lysis buffer and as a running buffer in electrophoresis
  • Used for protein purification in chromatography
  • Used as a buffer component of charcoal yeast extract medium
  • In personal care and cosmetics application, MOPS can protect active ingredients against degradation and functions as a buffer for gelling
  • It interacts with peptide backbone of bovine serum albumin leading to a net stabilization of the protein

Metal binding: (Compare with other buffers)

Strong interaction with:


Weak interaction with:

Mg, Mn, Co and Ni

Solubility in water: (Compare with other buffers)

  • 10g/100ml

Saturation at 0°C: (Compare with other buffers)

  • 3.00 M


  • Store at room temperature
Basic Information


Assay (titration)

≥ 99.5%

Useful pH range

6.5 – 7.9
Compare with other buffers

pKa (25°C)

7.0 – 7.4


White powder

Molecular formula


Molecular weight

209.3 g/mol

Solubility (33% in H2O)

Clear and Complete

Moisture (LOD)

≦ 1.0%

pH (1% in H2O)

3.6 – 4.4


In conformance with known standard

Heavy Metals (as Pb)

≦ 5 ppm

UV (1M in H2O) A260nm

≦ 0.05

UV (1M in H2O) A280nm

≦ 0.03

Customized specifications are available for bulk requests. Contact us to discuss your requirements.

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Synonyms / Similar names:

  • 3-(N-Morpholino)propanesulfonic acid
  • 4-Morpholinepropanesulfonic acid
  • MOPS Free Acid

What we offer:

  • Worldwide shipping
  • Certificate of Analysis (CoA)
  • Safety Data Sheet (SDS)
  • Analytical tests (DNase, RNase, protease activity, heavy metals and others upon request)


  • Product registered under the European Chemicals Agency's REACH regulation

Related products:

Useful pH range chart
Use our interactive chart below to compare the useful pH range of this product with other buffers’. Click in the product name to access more information about it.