What are the applications of biological buffers in the pharmaceutical field?

 

Many people can't go to the hospital because of their busy lives. If only got cold, most people choose to go to the pharmacy to buy medicines for relief and treatment.
In the dazzling array of drugs on the market, biological buffers may be used for the research process, development process, manufacturing processes, and final products.
What are the applications of biological buffers in the pharmaceutical field?
The following will list the actual application for you based on our observation of the market.

In the pharmaceutical field, biological buffers are usually used to maintain the specific pH value.

  • Ensure the stability of drug components: Maintain the pH value of essential components of the drug from being changed or degraded by the gastrointestinal environment, such as aspirin.
  • Improve the purity of specific components: Separate and purify specific components, such as insulin.
  • Ensure the solubility of the drug: Specific ingredients are only dissolved at a specific pH.
  • Ensure biological activity: Certain ingredients can only maintain their effective activity at a certain pH value, such as pepsin.
  • Enabling drugs to be used in the human body: Injections are close to the blood pH value; eye drops close to the eye environment.
  • As an active ingredient: The gastric acid inhibitor contains a buffer to reduce the acidity of the stomach.

HOPAX TRIS

HOPAX provides TRIS that conform to the requirement of USP, EP, BP, ChP, and is suitable for pharma and biopharmaceutical production and formulation.

  • TRIS is commonly used as a buffer for vaccines and antibiotics, such as fosfomycin trometamol.
  • Used in inflammation and pain after ophthalmic surgery.
  • Used as a biological buffer in a pharmaceutical excipient, commonly used for high-risk applications.
  • Used as an excipient in biologics and small molecule drugs formulated as parenteral drug products.
  • Used in ophthalmic solutions and topical drug products, as buffering and neutralization action.
Learn more about HOPAX TRIS

HOPAX HEPES

HOPAX produces high-quality HEPES and also provides HEPES cell culture grades that pass cytotoxicity testing.

  • As a radioactive excipient.
Learn more about HOPAX HEPES.

HOPAX HEPES NA

Hopax is a manufacturer and supplier of HEPES Sodium Salt.

  • As a pharmaceutical raw material.
Learn more about Hopax HEPES Na

HOPAX Glycylglycine

Glycylglycine is a dipeptide also used as a buffering agent in enzymatic assays and in medical procedures.

  • Maintain the pH value within a certain range.
Learn more about HOPAX Glycylglycine

Other ingredients commonly found in pharmaceutical industry applications.

  • Citric Acid: Injection, Kill harmful bacteria.
  • Phosphate: Injection.
  • Acetate: Injection.
  • Acetic acid: Vitamins, Antibiotics, Hormones, and other drugs.
  • Histidine: Used in protein preparations (Protein therapeutics).
  • Gluconic acid: Small molecule preparation.
  • Lactic acid: Small molecule preparation.
  • Tartaric acid: Small molecule preparation, excipients.
  • Aspartic acid: Protein preparation buffer.
  • Glutamic acid: Protein preparation buffer.
  • Citric acid cycle intermediate: As a buffer or counter ion in injection preparations, but maybe causes pain at the injection position.

Please CONTACT US for the high-quality BUFFERS!!

 

Release date:2021.01.15