The formula in the Pharmaceutical field-Pharma Grade Trometamol
Basic Information of TRIS Buffer
- Assay (titr.): ≥ 99%
- CAS No: 77-86-1
- Useful pH range: 7.2 – 9.0
- pKa (25°C): 7.8 – 8.2
- Appearance: White powder
- Molecular formula: C4H11NO3
- EC Number: 201-064-4
- interaction with: Cr, Fe, Co, Ni and Cu
- Weak interaction with: Mg, Ca, Zn, Cd, and Pb
HOPAX Capabilities
- This product meets the requirement of USP, EP, BP, ChP, and is suitable for pharma and biopharmaceutical production and formulation.
- This product has done the registration for REACH (Registration, Evaluation, Authorisation, and Restriction of Chemicals)
- This product is executed that the bioburden, endotoxin, heavy metals, and DNase/RNase/protease activity testing., etc.
- We are certified to ISO 9001, ISO45001, ISO14001.
The common Choice in the Bio-Tech!
- In buffer solutions for gel electrophoresis (TAE and TBE)
- In the preparation of Laemmli buffer, one of the most popular running buffers for SDS-PAGE
- As a binding buffer and eluent in anion exchange chromatography
- For the evaluation of bacterial endotoxins
- In capillary electrochromatography (CEC), since it has low ionic mobility
- Used as pH buffering of enzymes for biology technology.
- Used in the purification of biological molecules, such as monoclonal antibodies, recombinant proteins, and insulin for medical applications.
The formula in the Pharmaceutical field!
- In the pharmaceutical field, TRIS is commonly used as a buffer for vaccines and antibiotics, such as fosfomycin trometamol.
- This chemical is considered an excellent emulsifying agent and viscosity controller, and it is known for its capacity to maintain the original colors of lotions after opening.
- Used in inflammation and pain after ophthalmic surgery.
- Used as a biological buffer in a pharmaceutical excipient, commonly used for high-risk applications.
- Used as an excipient in biologics and small molecule drugs formulated as parenteral drug products.
- Used in ophthalmic solutions and topical drug products, as buffering and neutralization action.
The ingredients buffer for personal care and cosmetics!
- TRIS functions as a buffer and a mild neutralizing amine for skin and sun care formulations.
Further reading:The application of Sulfobutyl ether beta-cyclodextrin (SEβCD)
Further reading:What is Cyclodextrin?
Why choose HOPAX TRIS
As a professional biological buffer manufacturer, HOPAX produces high-quality TRIS (pharma grade) and provides special testing services, such as bioburden, endotoxin, heavy metals, and DNase/RNase/protease activity testing, etc., as per your applications. In addition, we also offer a variety of packaging options. In any case, HOPAX is absolutely the best choice for your purchase of TRIS!
Further reading:The uses of Tris buffer - A starting guide
For more details about the REACH compliance status of any HOPAX fine chemical products, please feel free to reach your business contacts at HOPAX Fine Chemicals Division or [email protected] for assistance.