Protein purification | Protein separation | Protein solubilization
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Assay (HPLC.): ≥97% | CAS No: 160788-56-7  

Hopax is among the world's largest manufacturers and suppliers of NDSB-221 (CAS 160788-56-7) with full chemical name as Dimethyl-2-hydroxyethylammoniumpropane sulfonate, is a nondetergent-sulfobetain(Additives for Protein Preparations).

Uses of NDSB-221:

  • This Good's buffer is a very popular buffering agent in microsomal protein extraction.
  • Used in nuclear protein recovery.
  • Used as precipitation reduction in IEF.
  • Used in membrane-bound protease purification.
  • Used in investigate an alternative strategy for crystallizing acromolecules
  • Used in assess halophilic protein stabilization research by the mild solubilizing agents nondetergent sulfobetaines.
  • Used to identify a novel ligand binding site in phosphoserine phosphatase from Thermococcus onnurineus, and also used to investigate its effects on acidic fibroblast growth factor (aFGF).

Characteristic of NDSB-221:

  • Easily removed by dialysis.
  • Over a wide pH range, it is zwitterionic.
  • In the near UV range, it shows no significant absorption.

Solubility in water:

  • 50 mg/mL in H2O

Molecular Weight:

  • 221.32 g/mol
Basic Information


Assay (HPLC)

≥ 97%


≦ 1%


White powder

Molecular formula


Molecular weight

221.32 g/mol

Customized specifications are available for bulk requests. Contact us to discuss your requirements.

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Synonyms / Similar names:

  • 3-(1-Methylpiperidinium)-1-propane sulfonate
  • 3-(1-Methylpiperidinio)-1-propanesulfonate

What we offer:

  • Certificate of Analysis (CoA)
  • Worldwide delivery
  • Small and bulk quantities available

Lead time

  • 15 business days after order confirmation