The formula in the Pharmaceutical field-Pharma Grade Trometamol
Basic Information of TRIS Buffer
- Assay (titr.): ≥ 99%
- CAS No: 77-86-1
- Useful pH range: 7.2 – 9.0
- pKa (25°C): 7.8 – 8.2
- Appearance: White powder
- Molecular formula: C4H11NO3
- EC Number: 201-064-4
- interaction with: Cr, Fe, Co, Ni and Cu
- Weak interaction with: Mg, Ca, Zn, Cd, and Pb
HOPAX Capabilities
- This product meets the requirement of USP, EP, BP, ChP, and is suitable for pharma and biopharmaceutical production and formulation.
- This product has done the registration for REACH (Registration, Evaluation, Authorisation, and Restriction of Chemicals)
- This product is executed that the bioburden, endotoxin, heavy metals, and DNase/RNase/protease activity testing., etc.
- We are certified to ISO 9001, ISO45001, ISO14001.
The common Choice in the Bio-Tech!
- In buffer solutions for gel electrophoresis (TAE and TBE)
- In the preparation of Laemmli buffer, one of the most popular running buffers for SDS-PAGE
- As a binding buffer and eluent in anion exchange chromatography
- For the evaluation of bacterial endotoxins
- In capillary electrochromatography (CEC), since it has low ionic mobility
- Used as pH buffering of enzymes for biology technology.
- Used in the purification of biological molecules, such as monoclonal antibodies, recombinant proteins, and insulin for medical applications.
The formula in the Pharmaceutical field!
- In the pharmaceutical field, TRIS is commonly used as a buffer for vaccines and antibiotics, such as fosfomycin trometamol.
- This chemical is considered an excellent emulsifying agent and viscosity controller, and it is known for its capacity to maintain the original colors of lotions after opening.
- Used in inflammation and pain after ophthalmic surgery.
- Used as a biological buffer in a pharmaceutical excipient, commonly used for high-risk applications.
- Used as an excipient in biologics and small molecule drugs formulated as parenteral drug products.
- Used in ophthalmic solutions and topical drug products, as buffering and neutralization action.
The ingredients buffer for personal care and cosmetics!
- TRIS functions as a buffer and a mild neutralizing amine for skin and sun care formulations.
Further reading:The application of Sulfobutyl ether beta-cyclodextrin (SEβCD)
Further reading:What is Cyclodextrin?
Why choose HOPAX TRIS
As a professional biological buffer manufacturer, HOPAX produces high-quality TRIS (pharma grade) and provides special testing services, such as bioburden, endotoxin, heavy metals, and DNase/RNase/protease activity testing, etc., as per your applications. In addition, we also offer a variety of packaging options. In any case, HOPAX is absolutely the best choice for your purchase of TRIS!
Further reading:The uses of Tris buffer - A starting guide
For more details about the REACH compliance status of any HOPAX fine chemical products, please feel free to reach your business contacts at HOPAX Fine Chemicals Division or HOPAXFC-CS@hopax.com.tw for assistance.