MOPS Buffer

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Cryopreservation media | Cell culture media | Chromatography | Cosmetics | Electrophoresis | Protein purification
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Assay (titr.): ≥ 99.5% | CAS No: 1132-61-2 | Useful pH range: 6.5 – 7.9 

Hopax is a manufacturer and supplier of MOPS (CAS 1132-61-2), a zwitterionic biological buffer often used as a buffering agent in biological and biochemical research.

Uses of MOPS Buffer:

  • Similarly to MES Buffer, this Good's Buffer lacks the capability to form a complex with most metal ions, therefore it is recommended for use as a noncoordinating buffer in solutions with metal ions
  • Used in cell culture media for yeast, bacteria and mammalian cells
  • Used for separating RNA in agarose gels
  • Used as a lysis buffer and as a running buffer in electrophoresis
  • Used for protein purification in chromatography
  • Used as a buffer component of charcoal yeast extract medium
  • In personal care and cosmetics application, MOPS can protect active ingredients against degradation and functions as a buffer for gelling
  • It interacts with peptide backbone of bovine serum albumin leading to a net stabilization of the protein


More about MOPS Buffer

Metal binding: (Compare with other buffers)

Strong interaction with:


Weak interaction with:

Mg, Mn, Co and Ni

Solubility in water: (Compare with other buffers)

  • 10g/100ml

Saturation at 0°C: (Compare with other buffers)

  • 3.00 M


  • Store at room temperature
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Assay (titration)

≥ 99.5%

Useful pH range

6.5 – 7.9
Compare with other buffers

pKa (25°C)

7.0 – 7.4


White powder

Molecular formula


Molecular weight

209.3 g/mol

Solubility (33% in H2O)

Clear and Complete

Moisture (LOD)

≦ 1.0%

pH (1% in H2O)

3.6 – 4.4


In conformance with known standard

Heavy Metals (as Pb)

≦ 5 ppm

UV (1M in H2O) A260nm

≦ 0.05

UV (1M in H2O) A280nm

≦ 0.03

Customized specifications are available for bulk requests. Contact us to discuss your requirements.

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Synonyms / Similar names:

  • 3-(N-Morpholino)propanesulfonic acid
  • 4-Morpholinepropanesulfonic acid
  • MOPS Free Acid

What we offer:

  • Worldwide shipping
  • Certificate of Analysis (CoA)
  • Safety Data Sheet (SDS)
  • Analytical tests (DNase, RNase, protease activity, heavy metals and others upon request)

Lead time:

  • 15 business days after order confirmation


  • Product registered under the European Chemicals Agency's REACH regulation

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