CAPS Buffer

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Cell culture media | Chromatography | Electrophoresis
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Assay (titr.): ≥ 99% | CAS No: 1135-40-6 | Useful pH range: 9.7 - 11.1 

Hopax is a manufacturer and supplier of CAPS (CAS 1135-40-6), a zwitterionic biological buffer often used as a buffering agent in biological and biochemical research.

Uses of CAPS Buffer:

  • Cation exchange chromatography
  • Capillary electrophoresis
  • Diffusion blotting and electroblotting
  • In the study of enzymatic processes above physiological pH
  • Used as an effective crystallization solution for different proteins
  • The longer carbon chain of the sulfonic acid group in CAPS gives it a slightly more alkaline range than CHES Buffer (also manufactured by Hopax)

Metal binding: (Compare with other buffers)

  • Negligible metal ion binding.

Solubility in water: (Compare with other buffers)

  • 5g/100ml

Saturation at 0°C: (Compare with other buffers)

  • 0.47 M


  • Store at room temperature
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Assay (titration)

≥ 99%

Useful pH range

9.7 - 11.1
Compare with other buffers

pKa (25°C)

10.2 - 10.6


White powder

Molecular formula


Molecular weight

221.32 g/mol

pH (1% in H2O)

4.9 – 6.0

UV (0.5M in H2O) A250nm 

≦ 0.05 

UV (0.5M in H2O)A280nm 

≦ 0.10
Customized specifications are available for bulk requests. Contact us to discuss your requirements.

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Synonyms / Similar names:

  • 3-(Cyclohexylamino)-1-propanesulfonic acid

What we offer:

  • Certificate of Analysis (CoA)
  • Small and bulk quantities available 
  • Analytical tests (DNase, RNase, protease activity, heavy metals and others upon request)


Lead time:

  • 15 business days after order confirmation